Pseudomonas aeruginosa, also known as Pseudomonas aeruginosa, is a common bacterium that causes chronic hospital-acquired infections. One of the ways P. aeruginosa causes infection is through Quorum Sensing (QS). QS is the secret language of bacteria that use small molecules, called autoinducers, instead of words. In this project, we propose tools for the rapid determination of autoinducers secreted by P. aeruginosa at the initial stage of bacterial colonisation, which[ ... ]

Osteomyelitis (OM - Latin for osteomyelitis) is an inflammation of bone tissue and bone marrow that is one of the most difficult bacterial infections to treat. The aim of the project is to obtain a carrier for two antibiotics - vancomycin and ciprofloxacin - for local drug delivery in the control of bone marrow and bone infection. A new approach is the use of organic-inorganic nano-flowers as a material mapping the structure of bone. 

Therapeutic drug monitoring (TDM) is the adjustment of a drug's dosage so that the concentration achieved is effective, while minimising side effects or toxicities. An example of a drug for which TDM is crucial is azathioprine, an immunosuppressive drug administered after organ transplantation and in the treatment of autoimmune diseases (e.g. lupus, rheumatoid arthritis, Crohn's disease). The aim of the project[ ... ]