{"id":900,"date":"2026-01-27T01:32:10","date_gmt":"2026-01-27T00:32:10","guid":{"rendered":"https:\/\/ibib.waw.pl\/?page_id=900"},"modified":"2026-03-19T15:07:52","modified_gmt":"2026-03-19T14:07:52","slug":"tematy-statutowe","status":"publish","type":"page","link":"https:\/\/ibib.waw.pl\/en\/nauka\/tematy-statutowe\/","title":{"rendered":"Statutory topics"},"content":{"rendered":"<section class=\"wp-block-custom-section regular\"><div class=\"container\">\n<h2 class=\"wp-block-heading\">Eight statutory topics are currently being pursued at the Institute:&nbsp;<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">1. <strong><span style=\"text-decoration: underline;\">Microbiosystems for diagnostics and personalized therapy<\/span><\/strong><\/h3>\n\n\n\n<p><strong>Head:<\/strong> Prof. Dorota G. Pijanowska<\/p>\n\n\n\n<p>Recent studies on therapy selection are based on drug susceptibility\/resistance analysis of specific cells. In vitro, liver cells, particularly hepatocytes, rapidly differentiate, losing their specific functions. We are investigating (1) the restoration of lost cellular functions using, among other things, genetic engineering methods, (2) the assessment of morphological and behavioural changes in cells and (3) methods for the determination of selected markers of cellular activity of hepatic origin, e.g. ammonia detoxification using lab-on-a chip microarrays for urea determination and biosensors for the assessment of arginase I enzymatic activity. In addition, we are working on analysing and recognising images of cells and stained tissue preparations to assist pathomorphologists.<\/p>\n\n\n\n<p>Carried out in the:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li><strong><a href=\"https:\/\/ibib.waw.pl\/en\/?page_id=3059\" data-type=\"page\" data-id=\"3059\">Laboratory of Tissue Engineering<\/a><\/strong><br><strong>Head: <\/strong>Krzysztof Pluta, PhD<\/li>\n\n\n\n<li><strong><a href=\"\/en\/zaklad-i-pracownia-2\/\">Laboratory of Microscopic Image Processing and Analysis Systems<\/a>\u2028<\/strong><br><strong>Head:<\/strong> Assoc. Prof. Anna Korzy\u0144ska, DSc. PhD<\/li>\n\n\n\n<li><strong><a href=\"\/en\/zaklad-1-pracownia-3\/\">Laboratory of Biosensors and Analytical Microsystems<\/a> <\/strong><br><strong>Head:<\/strong> Assoc. Prof. Kamila Sadowska, DSc. Phd<\/li>\n<\/ul>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section light-grey\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">2. <strong><span style=\"text-decoration: underline;\">Polymeric carriers for the construction of cellular scaffolds and delivery systems for biologically active substances<\/span><\/strong><\/h3>\n\n\n\n<p><strong>Head:<\/strong> Assoc. Prof. Dorota Lewi\u0144ska, DSc. PhD<\/p>\n\n\n\n<p>Since articular cartilage does not regenerate spontaneously, the most promising therapies use polymeric cellular scaffolds to host and multiply the patient's own cartilage cells. Our goal is therefore to develop innovative scaffolds that support the cultivation of chondrocytes, enabling the regeneration of damaged cartilage. The scaffolds we developed have been tested on animals.<br>The second research direction includes the development of  novel methods for the encapsulation of biologically active compounds, functional proteins or living cells. Techniques we work with include electrostatic fabrication of micro- and nano-sized capsules, electrospinning of polymer non-wovens and 3D bioprinting.<\/p>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-ii-pracownia-1\/\">Laboratory of Electrostatic Methods of Bioencapsulation<\/a> <\/strong><br><strong>Head:<\/strong> Assoc. Prof. Dorota Lewi\u0144ska, DSc. PhD&nbsp;<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section regular\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">Optoelectronic methods in the study of oxygenation and perfusion of tissues <\/h3>\n\n\n\n<p><strong>Head:<\/strong> Assoc. Prof. Piotr Sawosz, DSc. PhD; Stanis\u0142aw Wojtkiewicz, PhD<\/p>\n\n\n\n<p>The statutory subject includes two tasks:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>Development of theoretical methods to describe light propagation in tissues.<\/li>\n\n\n\n<li>New measurement methods for the assessment of oxygenation and perfusion of tissues.&nbsp;<\/li>\n<\/ol>\n\n\n\n<p>Ongoing research aims to develop new methods and optoelectronic devices to study oxygenation and perfusion of tissues, including areas of the brain undergoing functional stimulation. Selected application examples of ongoing research activities:<\/p>\n\n\n\n<ul class=\"wp-block-list\">\n<li>Non-invasive diagnosis of stroke, intracranial haemorrhage, intraoperative monitoring of cerebral oxygenation (e.g. carotid artery clog removal), detection of brain death, etc.&nbsp;<\/li>\n\n\n\n<li>Non-invasive imaging of cerebral cortex activity during movement or viewing of visual stimuli, also under oxygen deprivation or g-force overload conditions.<\/li>\n\n\n\n<li>Non-invasive monitoring of muscle oxygenation during exercise.<\/li>\n\n\n\n<li>Non-contact, non-invasive monitoring of wound healing using correlative speckle field imaging technique.<\/li>\n\n\n\n<li>Non-invasive monitoring of cerebral flow by diffuse correlation spectroscopy technique.<\/li>\n\n\n\n<li>Optical measurement of systolic and diastolic blood pressure.<\/li>\n\n\n\n<li>Tools for modelling light propagation in tissues that, when applied to a measurement method, allow for recovery of information on the oxygenation or blood supply of the tissue.<\/li>\n<\/ul>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-iii-pracownia-2\/\">Laboratory of Biomedical Optics<\/a>&nbsp;\u2028<\/strong><br><strong>Head:<\/strong> Stanis\u0142aw Wojtkiewicz, PhD<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section light-grey\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">Nanobiosystems for biological processes regulation for therapeutic purposes&nbsp;<\/h3>\n\n\n\n<p><strong>Head:<\/strong> Prof. Ludomira Granicka, DSc. PhD<\/p>\n\n\n\n<p>Wound healing is a serious problem in modern societies, which is deepened by coexisting civilization diseases. Nanobiomaterial engineering techniques are used in systems for biological processes regulation, for example for supporting and regenerating tissue functions. The research conducted is aimed at developing multilayer nanocomposite systems with a function supporting tissue regeneration and\/or antimicrobial, used to support healing at the skin-bone interface.<\/p>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-ii-pracownia-2\/\">Laboratory of Nanohybrid Biosystems Regulation Engineering<\/a><\/strong><br><strong>Head:<\/strong> Prof. Ludomira Granicka, DSc. PhD<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section regular\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">Systems for diagnostics, support or replacement of heart and respiratory functions<\/h3>\n\n\n\n<p><strong>Head:<\/strong>Krzysztof Zieli\u0144ski, PhD; Prof. Marek Darowski, DSc. PhD<\/p>\n\n\n\n<p>Deaths caused by heart and lung diseases are at the top of mortality for years both in Poland and worldwide. These diseases cause serious social and economic problems. An important type of their treatment is supporting the function of the lungs and heart, with particular emphasis on circulatory-respiratory interaction. The simulation studies conducted on these systems aim to better understand their physiology, optimize mechanical support therapy or improve the skills of medical personnel by training and education<\/p>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-iv-pracownia-1\/\">Cardiopulmonary Diagnostic and Therapy Support Laboratory<\/a>Head:<\/strong> Krzysztof Zieli\u0144ski, PhD<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section light-grey\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">6. Diagnostics and treatment support of metabolic diseases&nbsp;<\/h3>\n\n\n\n<p><strong>Head:<\/strong> Prof. Piotr \u0141ady\u017cy\u0144ski<\/p>\n\n\n\n<p>We develop and apply ICT and AI systems, biomeasurement techniques, metabolomics, mathematical and in vitro modeling, as well as hybrid methods combining artificial systems with living cells and tissues. These tools serve two main purposes:<\/p>\n\n\n\n<ol class=\"wp-block-list\">\n<li>To design and validate eHealth and decision support systems that aid in diagnosing and treating chronic metabolic diseases, such as diabetes and its complications.<\/li>\n\n\n\n<li>To investigate the pathophysiological mechanisms of metabolic disorders linked to conditions like neurodegenerative diseases.<\/li>\n<\/ol>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-iv-pracownia-2\/\">Laboratory of Diagnosis and Therapy Support of Metabolic Diseases<\/a> <\/strong><br><strong>Head:<\/strong> Assoc. Prof. Piotr Folty\u0144ski, DSc. PhD<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section regular\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">7. Applications of mathematical modeling in physiology and clinical research<\/h3>\n\n\n\n<p><strong>Head:<\/strong> Assoc. Prof. Joanna Stachowska-Pietka,  DSc. PhD<\/p>\n\n\n\n<p>Supporting research and therapeutic regulation of disturbed physiological processes through mathematical modeling contributes to the effective optimization of therapies and the accurate interpretation of associated complications. Our particular focus includes dialysis therapy (artificial kidney) and the cardiovascular system with analyses of arterial pulse wave. Examples of our current work include studying substance transport processes, mechanisms of blood pressure regulation, the acid-base balance of body fluids, and mineral metabolism in hemodialysis patients, as well as investigating tissue transport changes in patients undergoing peritoneal dialysis.<\/p>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-iv-pracownia-3\/\">Laboratory of Mathematical Modeling of Physiological Processes<\/a>&nbsp; <\/strong><br><strong>Head:<\/strong> Assoc. Prof. Joanna Stachowska-Pietka, PhD, DSc<\/p>\n<\/div><\/section>\n\n\n\n<section class=\"wp-block-custom-section light-grey\"><div class=\"container\">\n<h3 class=\"wp-block-heading\">8. Quantitative methods of biomedical research using the magnetic resonance technique&nbsp;<\/h3>\n\n\n\n<p><strong>Head: <\/strong>Prof. Piotr Bogorodzki<\/p>\n\n\n\n<p>CNSLab is an interdisciplinary research team specializing in structural and functional brain studies using advanced magnetic resonance imaging (MRI) techniques. The CNSLab team explores innovative methods such as spectroscopy and imaging of C13 and F19 nuclei for metabolic and chemical tissue analysis, simultaneous EEG-fMRI measurements, and diffusion-weighted imaging (DWI) for perfusion assessment and structural brain studies. CNSLab is equipped with a robust infrastructure supporting research and clinical experiments.<\/p>\n\n\n\n<p>Carried out in the <strong><a href=\"\/en\/zaklad-iii-pracownia-2-2\/\">Interinstitute Laboratory of new diagnostic applications of MRI<\/a> <\/strong><br><strong>Head: <\/strong>Prof. Piotr Bogorodzki, D.Sc. Ph.D.<\/p>\n<\/div><\/section>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":0,"parent":627,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-subpage-nobread.php","meta":{"_acf_changed":false,"_only_polish":false,"footnotes":""},"folder":[29],"class_list":["post-900","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/pages\/900","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/comments?post=900"}],"version-history":[{"count":14,"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/pages\/900\/revisions"}],"predecessor-version":[{"id":3102,"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/pages\/900\/revisions\/3102"}],"up":[{"embeddable":true,"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/pages\/627"}],"wp:attachment":[{"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/media?parent=900"}],"wp:term":[{"taxonomy":"folder","embeddable":true,"href":"https:\/\/ibib.waw.pl\/en\/wp-json\/wp\/v2\/folder?post=900"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}