We would like to invite you on Seminar of the Department III

Prof. Ewa Zalewska from Laboratory of Modeling and Electrophysiological Methods

will speak about: Relationship between muscle morphology and muscle bioelectrical activity biopsy versus motor unit potential

The seminar will take place in the Hall Professor A. Morecki, Thursday, November 14th at 11:30 pm.

The lecture presents results of the study on relationship between muscle morphology and muscle bioelectrical activity. The study were performed using the approximation method which principle rests upon decomposition of motor unit potentials (MUPs) into single fiber potentials (SFPs) to determine the morphology of muscle fibers generating these potentials i.e. their diameters and distribution within motor unit territory.
The aim was to compare muscle fiber diameters obtained from muscle biopsy and from recorded motor unit potentials (MUPs) analysis. Electromyography and muscle biopsy were performed in patients with a suspicion of a neuromuscular disorder. Histograms of the muscle fiber diameters determined from MUPs analysis were compared with those from biopsy.
The study was performed also on identification of components from distant fibers in recorded SFP. The criteria defining SFP in case of SFP contaminated by distant fibers were analyzed and the influence of the second fiber contamination on jitter and fiber diameter determination were analyzed.
The results suggest that contamination of other fibers may impact jitter measurement. The contamination tends to decrease the jitter as well as determined diameter. A new approach to the identification of SFP has been proposed.